Laparoscopic surgery is feasible and safe in selected patients with rectal cancer, with favorable short-term and mid-term outcomes. Recently, results of large randomized controlled trials comparing laparoscopic with conventional open surgery have been published, demonstrating that laparoscopic surgery for colon cancer was equivalent to open surgery in terms of postoperative complications and long-term outcomes. In this lecture, Professor Junji Okuda presents the laparoscopic approach for transverse colon cancer and shows the port and patient positioning, precious technical details when performing splenic flexure dissection and anatomical notes along with a demonstration video.