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LIVE INTERACTIVE SURGERY: Barrett's esophagus treatment using BARRX™ radiofrequency ablation (RFA) system

LL Swanström, MMD, FACS, FASGE, FRCSEng (Hon) V Wong, MD
Epublication WebSurg.com, Jan 2016;16(01). URL: http://websurg.com/doi/vd01en4687

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  • 2016-01-18
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Barrett’s esophagus is a metaplastic change in the lining mucosa of the esophagus in response to chronic GERD. The hallmark of specialized Barrett’s epithelium is mucus-secreting goblet cells (intestinal metaplasia). There is an increased risk of adenocarcinoma with intestinal metaplasia. BARRX™ is a new treatment option for Barrett’s esophagus which uses Radio frequency energy and minimizes the risk of developing cancer. Radio frequency energy is delivered via a catheter to the esophagus, lasts less than a second and creates superficial injury to the mucosa. Principle: To deliver high power (approx. 300 Watts) in a short period of time. This will allow the depth of penetration to ablate the epithelium and the muscularis mucosa without injuring the submucosa. Overall results are excellent with elimination of dysplasia in 80% of patients and stricture rate to less than 6%. Side effects: chest pain following the procedure, which can be treated with analgesics. Bleeding, infection, and perforation requiring surgery are some of the rare complications. Follow-up: endoscopy at 3 months and ablation repeated if required.